5-Amino-2-nitrobenzoic acid
- Product Name
- 5-Amino-2-nitrobenzoic acid
- CAS No.
- 13280-60-9
- Chemical Name
- 5-Amino-2-nitrobenzoic acid
- Synonyms
- ANBA;NSC 74455;TIMTEC-BB SBB008583;3-CARBOXY-4-NITROANILINE;(Purified) [for gamma-GT];5-Amino-2-nitrobenzoicaci;3-AMINO-6-NITROBENZOIC ACID;5-AMINO-2-NITROBENZOIC ACID;2-NITRO-5-AMINOBENZOIC ACID;Benzoic acid, 5-amino-2-nitro-
- CBNumber
- CB1738500
- Molecular Formula
- C7H6N2O4
- Formula Weight
- 182.13
- MOL File
- 13280-60-9.mol
5-Amino-2-nitrobenzoic acid Property
- Melting point:
- 236-238 °C (lit.)
- Boiling point:
- 481.3±35.0 °C(Predicted)
- Density
- 1.568±0.06 g/cm3(Predicted)
- vapor pressure
- 0-0Pa at 20-50℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO, Methanol
- pka
- 2.28±0.25(Predicted)
- form
- Solid
- color
- Yellow-Brown
- Water Solubility
- Insoluble
- BRN
- 2107512
- InChIKey
- KZZWQCKYLNIOBT-UHFFFAOYSA-N
- LogP
- -1.48 at pH7
- Surface tension
- 70.53mN/m at 1g/L and 20℃
- CAS DataBase Reference
- 13280-60-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-22-20/21/22
- Safety Statements
- 26-36/37/39-37/39-36
- WGK Germany
- 3
- HS Code
- 29224999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 564613
- Product name
- 5-Amino-2-nitrobenzoic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $58.4
- Updated
- 2024/03/01
- Product number
- A0897
- Product name
- 5-Amino-2-nitrobenzoic Acid
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $72
- Updated
- 2024/03/01
- Product number
- A0897
- Product name
- 5-Amino-2-nitrobenzoic Acid
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $254
- Updated
- 2024/03/01
- Product number
- L16225
- Product name
- 5-Amino-2-nitrobenzoic acid, 95%
- Packaging
- 5g
- Price
- $92.3
- Updated
- 2024/03/01
- Product number
- L16225
- Product name
- 5-Amino-2-nitrobenzoic acid, 95%
- Packaging
- 1g
- Price
- $29.8
- Updated
- 2021/12/16
5-Amino-2-nitrobenzoic acid Chemical Properties,Usage,Production
Description
5-Amino-2-nitrobenzoic acid is a reagent used in preparation of polymer-bound diazonium salts and insulin receptor tyrosine kinase activator. It is also used in 2-component dendritic chain reactions and activation of hydrophobic dendrimers.
Chemical Properties
5-Amino-2-nitrobenzoic acid appears as a yellow powder or crystal. Its crystal structure is: the 5-amino-2-nitrobenzoic acid crystallizes in the monoclinic P21/c space group with a = 3.898(2)?, b = 13.531(3)?, c = 14.301(3) ?, and β = 90.83(3)?. The adjacent molecules form a cyclic dimmer by intermolecular hydrogen bonds of type O H···O with their carboxyl groups. In the crystal structure NH2 group forms a threecenter hydrogen bond with oxygen atoms of NO2 group.
Uses
5-Amino-2-nitrobenzoic acid can be used as a standard for the determination of γ-GT activity using 5-amino-2-nitrobenzoic acid as a standard. 5-Amino-2-nitrobenzoic acid (ANB) can also be used for spectroscopic studies by determining the FTIR and FT-Raman spectra of ANB in the 400-4000 cm-1 range and calculating the theoretically constructed spectra in good agreement with the experimental spectra.
Uses
Reactant for:
- Two-component dendritic chain reactions
- Enzymic activation of hydrophobic self-immolative dendrimers
- Preparation of insulin receptor tyrosine kinase activator
- Preparation of polymer-bound diazonium salts using Merrifield resin-bound piperazine
Application
5-Amino-2-nitrobenzoic acid is a drug that has been shown to inhibit the activity of proteases. It has been used to detect the presence of protease activity in urine samples, as well as to study the inhibition of protease activity by other drugs. It is an inhibitor of chymotrypsin, trypsin, and elastase. This drug has been shown to be effective in inhibiting these enzymes at low concentrations, with a detection sensitivity of approximately 0.1 μM. It inhibits the growth of bacteria by binding to them and preventing protein synthesis. The compound also inhibits the enzyme dihydrolipoamide dehydrogenase in mitochondria, which is required for cellular respiration and energy production.
Purification Methods
Crystallise the acid from water. [Beilstein 14 III 1021.]
5-Amino-2-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5-Amino-2-nitrobenzoic acid Suppliers
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View Lastest Price from 5-Amino-2-nitrobenzoic acid manufacturers
- Product
- 5-Amino-2-nitrobenzoic acid 13280-60-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2023-03-21
- Product
- 5-Amino-2-nitrobenzoic acid 13280-60-9
- Price
- US $34.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000 tons
- Release date
- 2023-03-08
- Product
- 5-Amino-2-nitrobenzoic acid 13280-60-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11